Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses

The cross-talk between the microbiota and the immune system plays a fundamental role in the control of host physiology. However, the tissue-specific factors controlling this dialogue remain poorly understood. Here we demonstrate that T cell responses to commensal colonization are associated with the...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tamoutounour, Samira, Han, Seong-Ji, Deckers, Julie, Constantinides, Michael G., Hurabielle, Charlotte, Harrison, Oliver J., Bouladoux, Nicolas, Linehan, Jonathan L., Link, Verena M., Vujkovic-Cvijin, Ivan, Perez-Chaparro, Paula Juliana, Rosshart, Stephan P., Rehermann, Barbara, Lazarevic, Vanja, Belkaid, Yasmine
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876208/
https://ncbi.nlm.nih.gov/pubmed/31672911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912432116
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