Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N(6)-methyladenosine of Notch1

BACKGROUND: N(6)-methyladenosine (m(6)A) emerges as one of the most important modification of RNA. Bladder cancer is a common cancer type in developed countries, and hundreds of thousands of bladder cancer patients die every year. MATERIALS AND METHODS: There are various cells in bladder tumor bulk,...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Gu, Chaohui, Wang, Zhiyu, Zhou, Naichun, Li, Guanru, Kou, Yiping, Luo, Yang, Wang, Yidi, Yang, Jinjian, Tian, Fengyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876123/
https://ncbi.nlm.nih.gov/pubmed/31760940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1084-1
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