DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism

Racial/ethnic disparities have a significant impact on bladder cancer outcomes with African American patients demonstrating inferior survival over European-American patients. We hypothesized that epigenetic difference in methylation of tumor DNA is an underlying cause of this survival health dispari...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Vantaku, Venkatrao, Amara, Chandra Sekhar, Piyarathna, Danthasinghe Waduge Badrajee, Donepudi, Sri Ramya, Ambati, Chandrashekar R, Putluri, Vasanta, Tang, Wei, Rajapakshe, Kimal, Estecio, Marcos Roberto, Terris, Martha K, Castro, Patricia D, Ittmann, Michael M, Williams, Stephen B, Lerner, Seth P, Sreekumar, Arun, Bollag, Roni, Coarfa, Cristian, Kornberg, Michael D, Lotan, Yair, Ambs, Stefan, Putluri, Nagireddy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Cancer Biomarkers and Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875901/
https://ncbi.nlm.nih.gov/pubmed/31284295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz128
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