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DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism

Racial/ethnic disparities have a significant impact on bladder cancer outcomes with African American patients demonstrating inferior survival over European-American patients. We hypothesized that epigenetic difference in methylation of tumor DNA is an underlying cause of this survival health dispari...

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Bibliografski detalji
Izdano u:Carcinogenesis
Glavni autori: Vantaku, Venkatrao, Amara, Chandra Sekhar, Piyarathna, Danthasinghe Waduge Badrajee, Donepudi, Sri Ramya, Ambati, Chandrashekar R, Putluri, Vasanta, Tang, Wei, Rajapakshe, Kimal, Estecio, Marcos Roberto, Terris, Martha K, Castro, Patricia D, Ittmann, Michael M, Williams, Stephen B, Lerner, Seth P, Sreekumar, Arun, Bollag, Roni, Coarfa, Cristian, Kornberg, Michael D, Lotan, Yair, Ambs, Stefan, Putluri, Nagireddy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875901/
https://ncbi.nlm.nih.gov/pubmed/31284295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz128
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