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How RNA structure dictates the usage of a critical exon of spinal muscular atrophy gene

Role of RNA structure in pre-mRNA splicing has been implicated for several critical exons associated with genetic disorders. However, much of the structural studies linked to pre-mRNA splicing regulation are limited to terminal stem-loop structures (hairpins) sequestering splice sites. In few instan...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gene Regul Mech
Main Authors: Singh, Natalia N., Singh, Ravindra N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875630/
https://ncbi.nlm.nih.gov/pubmed/31323435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2019.07.004
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