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H-Ferritin Affects Cisplatin-Induced Cytotoxicity in Ovarian Cancer Cells through the Modulation of ROS

Reactive oxygen species (ROS) mediates cisplatin-induced cytotoxicity in tumor cells. However, when cisplatin-induced ROS do not reach cytotoxic levels, cancer cells may develop chemoresistance. This phenomenon can be attributed to the inherited high expression of antioxidant protein network. H-Ferr...

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Publicat a:Oxid Med Cell Longev
Autors principals: Salatino, Alessandro, Aversa, Ilenia, Battaglia, Anna Martina, Sacco, Alessandro, Di Vito, Anna, Santamaria, Gianluca, Chirillo, Roberta, Veltri, Pierangelo, Tradigo, Giuseppe, Di Cello, Annalisa, Venturella, Roberta, Biamonte, Flavia, Costanzo, Francesco
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875340/
https://ncbi.nlm.nih.gov/pubmed/31781333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3461251
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