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MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer

Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer (EOC). In particular, some of the let-7 miRNA family members have been proposed as tumor suppressors. Here, we explored the functional roles of let-7g in EOC. The ectopic overexpression of let-7g in OVCAR3 and HE...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Biamonte, Flavia, Santamaria, Gianluca, Sacco, Alessandro, Perrone, Francesca Marta, Di Cello, Annalisa, Battaglia, Anna Martina, Salatino, Alessandro, Di Vito, Anna, Aversa, Ilenia, Venturella, Roberta, Zullo, Fulvio, Costanzo, Francesco
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450929/
https://ncbi.nlm.nih.gov/pubmed/30952937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42221-x
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