MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer

Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer (EOC). In particular, some of the let-7 miRNA family members have been proposed as tumor suppressors. Here, we explored the functional roles of let-7g in EOC. The ectopic overexpression of let-7g in OVCAR3 and HE...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Biamonte, Flavia, Santamaria, Gianluca, Sacco, Alessandro, Perrone, Francesca Marta, Di Cello, Annalisa, Battaglia, Anna Martina, Salatino, Alessandro, Di Vito, Anna, Aversa, Ilenia, Venturella, Roberta, Zullo, Fulvio, Costanzo, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450929/
https://ncbi.nlm.nih.gov/pubmed/30952937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42221-x
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