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Steady-State Plasma Concentrations of Polyethylene Glycol (PEG) are Reached in Children and Adults During Once-Weekly Prophylactic Treatment with Nonacog Beta Pegol (N9-GP)
BACKGROUND: Nonacog beta pegol (N9-GP, Refixia(®), Rebinyn(®)) is a human recombinant coagulation factor IX (rFIX) conjugated to a 40-kDa polyethylene glycol (PEG) moiety. PEGylation significantly prolongs the circulation half-life compared with conventional FIX replacement treatments, resulting in...
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| Publicado no: | BioDrugs |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6875145/ https://ncbi.nlm.nih.gov/pubmed/31549312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-019-00380-3 |
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