Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction

Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their properties, especially their poor stability, render them sub-optimal for use in a bioindustrial pipeline. Here, we employed ancestral sequence reconstruction (ASR) – a burgeoning engineering tool that can identify sta...

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Udgivet i:Commun Biol
Main Authors: Thomas, Adam, Cutlan, Rhys, Finnigan, William, van der Giezen, Mark, Harmer, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874671/
https://ncbi.nlm.nih.gov/pubmed/31799431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0677-y
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