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Reconstruction of ancestral protein sequences and its applications

BACKGROUND: Modern-day proteins were selected during long evolutionary history as descendants of ancient life forms. In silico reconstruction of such ancestral protein sequences facilitates our understanding of evolutionary processes, protein classification and biological function. Additionally, rec...

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Detalhes bibliográficos
Main Authors: Cai, Wei, Pei, Jimin, Grishin, Nick V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522809/
https://ncbi.nlm.nih.gov/pubmed/15377393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-4-33
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