Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

Extracellular vesicles (EVs) released by cells play a role in intercellular communication. Reporter and targeting proteins can be modified and exposed on the surface of EVs to investigate their half-life and biodistribution. A characterization of membrane-bound Gaussia luciferase (mbGluc) revealed t...

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Опубликовано в: :Sci Rep
Главные авторы: Zaborowski, Mikołaj Piotr, Cheah, Pike See, Zhang, Xuan, Bushko, Isabella, Lee, Kyungheon, Sammarco, Alessandro, Zappulli, Valentina, Maas, Sybren Lein Nikola, Allen, Ryan M., Rumde, Purva, György, Bence, Aufiero, Massimo, Schweiger, Markus W., Lai, Charles Pin- Kuang, Weissleder, Ralph, Lee, Hakho, Vickers, Kasey C., Tannous, Bakhos A., Breakefield, Xandra O.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874653/
https://ncbi.nlm.nih.gov/pubmed/31758005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53554-y
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