Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

Extracellular vesicles (EVs) released by cells play a role in intercellular communication. Reporter and targeting proteins can be modified and exposed on the surface of EVs to investigate their half-life and biodistribution. A characterization of membrane-bound Gaussia luciferase (mbGluc) revealed t...

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Publicado no:Sci Rep
Main Authors: Zaborowski, Mikołaj Piotr, Cheah, Pike See, Zhang, Xuan, Bushko, Isabella, Lee, Kyungheon, Sammarco, Alessandro, Zappulli, Valentina, Maas, Sybren Lein Nikola, Allen, Ryan M., Rumde, Purva, György, Bence, Aufiero, Massimo, Schweiger, Markus W., Lai, Charles Pin- Kuang, Weissleder, Ralph, Lee, Hakho, Vickers, Kasey C., Tannous, Bakhos A., Breakefield, Xandra O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874653/
https://ncbi.nlm.nih.gov/pubmed/31758005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53554-y
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