Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells

Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths, but its molecular mechanisms are not yet well characterized. Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis, including that of HCC. However, the role of homeobox A11 antisense (HOXA11-AS) in determining HCC...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Guo, Jun-Cheng, Yang, Yi-Jun, Zheng, Jin-Fang, Zhang, Jian-Quan, Guo, Min, Yang, Xiang, Jiang, Xiang-Ling, Xiang, Li, Li, You, Ping, Huang, Zhuo, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874533/
https://ncbi.nlm.nih.gov/pubmed/31757938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0328-x
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