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Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity
Apoptotic caspases evolved with metazoans more than 950 million years ago (MYA), and a series of gene duplications resulted in two subfamilies consisting of initiator and effector caspases. The effector caspase genes (caspases-3, -6, and -7) were subsequently fixed into the Chordata phylum more than...
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| 出版年: | Biochem J |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874516/ https://ncbi.nlm.nih.gov/pubmed/31675069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190625 |
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