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Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3
Caspase (or cysteinyl-aspartate specific proteases) enzymes play important roles in apoptosis and inflammation, and the non-identical but overlapping specificity profiles (that is, cleavage recognition sequence) direct cells to different fates. Although all caspases prefer aspartate at the P1 positi...
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| Publicado no: | Biosci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846959/ https://ncbi.nlm.nih.gov/pubmed/33448281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203495 |
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