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Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin
Protein phosphatase 2A (PP2A) is the major tau phosphatase. Its activity toward tau is regulated by the methylation of PP2A catalytic subunit (PP2Ac) at Leu309. Protein phosphatase methylesterase-1 (PME-1) demethylates PP2Ac and suppresses its activity. We previously found that glycogen synthase kin...
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| Publicado no: | Aging (Albany NY) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874473/ https://ncbi.nlm.nih.gov/pubmed/31714894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102413 |
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