NEDD4 family ubiquitin ligases associate with LCMV Z’s PPXY domain and are required for virus budding, but not via direct ubiquitination of Z

Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission during viral budding. Unlike the P(S/T)AP and YPX((1–3))L late domains, which interact directly with the ESCRT proteins Tsg101 and ALIX, the molec...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Ziegler, Christopher M., Dang, Loan, Eisenhauer, Philip, Kelly, Jamie A., King, Benjamin R., Klaus, Joseph P., Manuelyan, Inessa, Mattice, Ethan B., Shirley, David J., Weir, Marion E., Bruce, Emily A., Ballif, Bryan A., Botten, Jason
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874086/
https://ncbi.nlm.nih.gov/pubmed/31710650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008100
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