A novel phosphoserine motif in the LCMV matrix protein Z regulates the release of infectious virus and defective interfering particles

We report that the lymphocytic choriomeningitis virus (LCMV) matrix protein, which drives viral budding, is phosphorylated at serine 41 (S41). A recombinant (r)LCMV bearing a phosphomimetic mutation (S41D) was impaired in infectious and defective interfering (DI) particle release, while a non-phosph...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Ziegler, Christopher M., Eisenhauer, Philip, Bruce, Emily A., Beganovic, Vedran, King, Benjamin R., Weir, Marion E., Ballif, Bryan A., Botten, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756487/
https://ncbi.nlm.nih.gov/pubmed/27421645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000550
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