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Mathematical Approach to Differentiate Spontaneous and Induced Evolution to Drug Resistance During Cancer Treatment
PURPOSE: Drug resistance is a major impediment to the success of cancer treatment. Resistance is typically thought to arise from random genetic mutations, after which mutated cells expand via Darwinian selection. However, recent experimental evidence suggests that progression to drug resistance need...
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| Publicado no: | JCO Clin Cancer Inform |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6873992/ https://ncbi.nlm.nih.gov/pubmed/30969799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.18.00087 |
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