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Impairment of NKG2D-Mediated Tumor Immunity by TGF-β

Transforming growth factor-β (TGF-β) suppresses innate and adaptive immune responses via multiple mechanisms. TGF-β also importantly contributes to the formation of an immunosuppressive tumor microenvironment thereby promoting tumor growth. Amongst others, TGF-β impairs tumor recognition by cytotoxi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lazarova, Mariya, Steinle, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873348/
https://ncbi.nlm.nih.gov/pubmed/31803194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02689
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