Glucoselysine is derived from fructose and accumulates in the eye lens of diabetic rats

Prolonged hyperglycemia generates advanced glycation end-products (AGEs), which are believed to be involved in the pathogenesis of diabetic complications. In the present study, we developed a polyclonal antibody against fructose-modified proteins (Fru-P antibody) and identified its epitope as glucos...

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Vydáno v:J Biol Chem
Hlavní autoři: Ohno, Rei-ichi, Ichimaru, Kenta, Tanaka, Seitaro, Sugawa, Hikari, Katsuta, Nana, Sakake, Shiori, Tominaga, Yu-ki, Ban, Ikuho, Shirakawa, Jun-ichi, Yamaguchi, Yoshiki, Ito, Emi, Taniguchi, Naoyuki, Nagai, Ryoji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873178/
https://ncbi.nlm.nih.gov/pubmed/31594865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010744
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