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Off-Target Effects in Transgenic Mice: Characterization of Dopamine Transporter (DAT)-Cre Transgenic Mouse Lines Exposes Multiple Non-Dopaminergic Neuronal Clusters Available for Selective Targeting within Limbic Neurocircuitry

Transgenic mouse lines are instrumental in our attempt to understand brain function. Promoters driving transgenic expression of the gene encoding Cre recombinase are crucial to ensure selectivity in Cre-mediated targeting of floxed alleles using the Cre-Lox system. For the study of dopamine (DA) neu...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Papathanou, Maria, Dumas, Sylvie, Pettersson, Hanna, Olson, Lars, Wallén-Mackenzie, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873162/
https://ncbi.nlm.nih.gov/pubmed/31481399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0198-19.2019
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