Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

Chronic liver disease due to alcohol use disorder contributes markedly to the global burden of disease and mortality(1–3). Alcoholic hepatitis is a severe and life-threatening form of alcohol-associated liver disease. The gut microbiota promotes ethanol-induced liver disease in mice(4), but little i...

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Publicado no:Nature
Main Authors: Duan, Yi, Llorente, Cristina, Lang, Sonja, Brandl, Katharina, Chu, Huikuan, Jiang, Lu, White, Richard C., Clarke, Thomas H., Nguyen, Kevin, Torralba, Manolito, Shao, Yan, Liu, Jinyuan, Hernandez-Morales, Adriana, Lessor, Lauren, Rahman, Imran R., Miyamoto, Yukiko, Ly, Melissa, Gao, Bei, Sun, Weizhong, Kiesel, Roman, Hutmacher, Felix, Lee, Suhan, Ventura-Cots, Meritxell, Bosques-Padilla, Francisco, Verna, Elizabeth C., Abraldes, Juan G., Brown, Robert S., Vargas, Victor, Altamirano, Jose, Caballería, Juan, Shawcross, Debbie L., Ho, Samuel B., Louvet, Alexandre, Lucey, Michael R., Mathurin, Philippe, Garcia-Tsao, Guadalupe, Bataller, Ramon, Tu, Xin M., Eckmann, Lars, van der Donk, Wilfred A., Young, Ry, Lawley, Trevor D., Stärkel, Peter, Pride, David, Fouts, Derrick E., Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872939/
https://ncbi.nlm.nih.gov/pubmed/31723265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1742-x
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