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Furin-Mediated Intracellular Self-Assembly of Olsalazine Nanoparticles for Enhanced Magnetic Resonance Imaging and Tumor Therapy

One strategy to enhance tumor retention of imaging agents or anti-cancer drugs is rational design of probes that undergo a tumor-specific enzymatic reaction which prevents them from being pumped out of the cell. Here, the anticancer agent olsalazine (Olsa) was conjugated to the cell-penetrating pept...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Mater
Main Authors: Yuan, Yue, Zhang, Jia, Qi, Xiaoliang, Li, Shuoguo, Liu, Guanshu, Siddhanta, Soumik, Barman, Ishan, Song, Xiaolei, McMahon, Michael T., Bulte, Jeff W.M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872935/
https://ncbi.nlm.nih.gov/pubmed/31636420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0503-4
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