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Inherited and Sporadic Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degenerations arising from Pathological Condensates of Phase Separating Proteins

Recent work on the biophysics of proteins with low complexity, intrinsically disordered domains that have the capacity to form biological condensates has profoundly altered the concepts about the pathogenesis of inherited and sporadic neurodegenerative disorders associated with pathological accumula...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Fernandopulle, Michael, Wang, GuoZhen, Nixon-Abell, Jonathon, Qamar, Seema, Balaji, Varun, Morihara, Ryuta, St George-Hyslop, Peter H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872449/
https://ncbi.nlm.nih.gov/pubmed/31595953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz162
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