Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis

Mutations in GATA1, which lead to expression of the GATA1s isoform that lacks the GATA1 N terminus, are seen in patients with Diamond-Blackfan anemia (DBA). In our efforts to better understand the connection between GATA1s and DBA, we comprehensively studied erythropoiesis in Gata1s mice. Defects in...

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Опубликовано в: :Blood
Главные авторы: Ling, Te, Birger, Yehudit, Stankiewicz, Monika J., Ben-Haim, Nissim, Kalisky, Tomer, Rein, Avigail, Kugler, Eitan, Chen, Wei, Fu, Chunling, Zhang, Kevin, Patel, Hiral, Sikora, Jacek W., Goo, Young Ah, Kelleher, Neil, Zou, Lihua, Izraeli, Shai, Crispino, John D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2019
Предметы:
Red Cells, Iron, and Erythropoiesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871310/
https://ncbi.nlm.nih.gov/pubmed/31409672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001234
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