Brain region binding of the D(2/3) agonist [(11)C]‐(+)‐PHNO and the D(2/3) antagonist [(11)C]raclopride in healthy humans

The D(2) receptors exist in either the high‐ or low‐affinity state with respect to agonists, and while agonists bind preferentially to the high‐affinity state, antagonists do not distinguish between the two states. [(11)C]‐(+)‐PHNO is a PET D(2) agonist radioligand and therefore provides a preferent...

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Bibliografiske detaljer
Udgivet i:Hum Brain Mapp
Main Authors: Graff‐Guerrero, Ariel, Willeit, Matthaeus, Ginovart, Nathalie, Mamo, David, Mizrahi, Romina, Rusjan, Pablo, Vitcu, Irina, Seeman, Philip, Wilson, Alan A., Kapur, Shitij
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2007
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6870740/
https://ncbi.nlm.nih.gov/pubmed/17497628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.20392
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