Brain region binding of the D(2/3) agonist [(11)C]‐(+)‐PHNO and the D(2/3) antagonist [(11)C]raclopride in healthy humans

The D(2) receptors exist in either the high‐ or low‐affinity state with respect to agonists, and while agonists bind preferentially to the high‐affinity state, antagonists do not distinguish between the two states. [(11)C]‐(+)‐PHNO is a PET D(2) agonist radioligand and therefore provides a preferent...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Graff‐Guerrero, Ariel, Willeit, Matthaeus, Ginovart, Nathalie, Mamo, David, Mizrahi, Romina, Rusjan, Pablo, Vitcu, Irina, Seeman, Philip, Wilson, Alan A., Kapur, Shitij
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6870740/
https://ncbi.nlm.nih.gov/pubmed/17497628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.20392
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