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Low temperature isothermal amplification of microsatellites drastically reduces stutter artifact formation and improves microsatellite instability detection in cancer

Microsatellites are polymorphic short tandem repeats of 1–6 nucleotides ubiquitously present in the genome that are extensively used in living organisms as genetic markers and in oncology to detect microsatellite instability (MSI). While the standard analysis method of microsatellites is based on PC...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Daunay, Antoine, Duval, Alex, Baudrin, Laura G, Buhard, Olivier, Renault, Victor, Deleuze, Jean-François, How-Kit, Alexandre
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868440/
https://ncbi.nlm.nih.gov/pubmed/31584085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz811
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