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funtrp: identifying protein positions for variation driven functional tuning

Evaluating the impact of non-synonymous genetic variants is essential for uncovering disease associations and mechanisms of evolution. An in-depth understanding of sequence changes is also fundamental for synthetic protein design and stability assessments. However, the variant effect predictor perfo...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Miller, Maximilian, Vitale, Daniel, Kahn, Peter C, Rost, Burkhard, Bromberg, Yana
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868392/
https://ncbi.nlm.nih.gov/pubmed/31584091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz818
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