Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage

The addition of poly(ADP-ribose) (PAR) chains along the chromatin fiber due to PARP1 activity regulates the recruitment of multiple factors to sites of DNA damage. In this manuscript, we investigated how, besides direct binding to PAR, early chromatin unfolding events controlled by PAR signaling con...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Smith, Rebecca, Lebeaupin, Théo, Juhász, Szilvia, Chapuis, Catherine, D’Augustin, Ostiane, Dutertre, Stéphanie, Burkovics, Peter, Biertümpfel, Christian, Timinszky, Gyula, Huet, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868358/
https://ncbi.nlm.nih.gov/pubmed/31566235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz820
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