Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage

The addition of poly(ADP-ribose) (PAR) chains along the chromatin fiber due to PARP1 activity regulates the recruitment of multiple factors to sites of DNA damage. In this manuscript, we investigated how, besides direct binding to PAR, early chromatin unfolding events controlled by PAR signaling con...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Smith, Rebecca, Lebeaupin, Théo, Juhász, Szilvia, Chapuis, Catherine, D’Augustin, Ostiane, Dutertre, Stéphanie, Burkovics, Peter, Biertümpfel, Christian, Timinszky, Gyula, Huet, Sébastien
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868358/
https://ncbi.nlm.nih.gov/pubmed/31566235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz820
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