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Intravitreal injection of adenosine A(2A) receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice
Diabetic retinopathy is a major complication of diabetes mellitus and a leading cause of blindness. The pathogenesis of diabetic retinopathy is accompanied by chronic low-grade inflammation. Evidence shows that the blockade of adenosine A(2A) receptors (A(2A)R) affords protection to the retina throu...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868354/ https://ncbi.nlm.nih.gov/pubmed/31748653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53627-y |
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