Adenosine A(2A)R blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure

BACKGROUND: Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a degenerative disease characterized by the loss of retinal ganglion cells (RGCs). There is clinical and experimental evidence that neuroinflammation is involved in the pathogenesis of glaucoma. Since the blockade o...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Madeira, Maria H., Elvas, Filipe, Boia, Raquel, Gonçalves, Francisco Q., Cunha, Rodrigo A., Ambrósio, António Francisco, Santiago, Ana Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465153/
https://ncbi.nlm.nih.gov/pubmed/26054642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0333-5
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