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Phase I trials as valid therapeutic options for patients with cancer

For many years, oncology phase I trials have been referred to as ‘toxicity trials’ and have been believed to have low clinical utility other than that of establishing the adverse event profile of novel therapeutic agents. The traditional distinction of clinical trials into three phases has been chal...

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Bibliografiske detaljer
Udgivet i:Nat Rev Clin Oncol
Main Authors: Adashek, Jacob J., LoRusso, Patricia M., Hong, David S., Kurzrock, Razelle
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868302/
https://ncbi.nlm.nih.gov/pubmed/31477881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0262-9
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