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Phase I trials as valid therapeutic options for patients with cancer

For many years, oncology phase I trials have been referred to as ‘toxicity trials’ and have been believed to have low clinical utility other than that of establishing the adverse event profile of novel therapeutic agents. The traditional distinction of clinical trials into three phases has been chal...

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Pubblicato in:Nat Rev Clin Oncol
Autori principali: Adashek, Jacob J., LoRusso, Patricia M., Hong, David S., Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868302/
https://ncbi.nlm.nih.gov/pubmed/31477881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0262-9
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