Structural determinants of microtubule minus end preference in CAMSAP CKK domains

CAMSAP/Patronins regulate microtubule minus-end dynamics. Their end specificity is mediated by their CKK domains, which we proposed recognise specific tubulin conformations found at minus ends. To critically test this idea, we compared the human CAMSAP1 CKK domain (HsCKK) with a CKK domain from Naeg...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Atherton, Joseph, Luo, Yanzhang, Xiang, Shengqi, Yang, Chao, Rai, Ankit, Jiang, Kai, Stangier, Marcel, Vemu, Annapurna, Cook, Alexander D., Wang, Su, Roll-Mecak, Antonina, Steinmetz, Michel O., Akhmanova, Anna, Baldus, Marc, Moores, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868217/
https://ncbi.nlm.nih.gov/pubmed/31748546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13247-6
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