Hyperexcitability and impaired intracortical inhibition in patients with fragile-X syndrome

Fragile-X syndrome (FXS) is characterized by neurological and psychiatric problems symptomatic of cortical hyperexcitability. Recent animal studies identified deficient γ-aminobutyricacid (GABA) inhibition as a key mechanism for hyperexcitability in FXS, but the GABA system remains largely unexplore...

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Bibliographic Details
Published in:Transl Psychiatry
Main Authors: Morin-Parent, Florence, Champigny, Camille, Lacroix, Angelina, Corbin, François, Lepage, Jean-François
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868148/
https://ncbi.nlm.nih.gov/pubmed/31748507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0650-z
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