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PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions

P21-activated kinases (PAK) are key effectors of the small GTPases Rac1 and Cdc42, as well as of Src family kinases. In particular, PAK1 has several well-documented roles, both kinase-dependent and kinase-independent, in cancer-related processes, such as cell proliferation, adhesion, and migration....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Grebeňová, Dana, Holoubek, Aleš, Röselová, Pavla, Obr, Adam, Brodská, Barbora, Kuželová, Kateřina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868145/
https://ncbi.nlm.nih.gov/pubmed/31748572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53665-6
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