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Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin

Attachment of stem leukemic cells to the bone marrow extracellular matrix increases their resistance to chemotherapy and contributes to the disease persistence. In chronic myelogenous leukemia (CML), the activity of the fusion BCR-ABL kinase affects adhesion signaling. Using real-time monitoring of...

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Detalhes bibliográficos
Main Authors: Obr, Adam, Röselová, Pavla, Grebeňová, Dana, Kuželová, Kateřina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157868/
https://ncbi.nlm.nih.gov/pubmed/25198091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107367
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