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Pharmacokinetics of Exenatide in nonhuman primates following its administration in the form of sustained-release PT320 and Bydureon

The time-dependent (30 min - day 84) plasma profile of PT320, a sustained-release (SR)-Exenatide formulation under clinical development for treatment of neurodegenerative disorders, was evaluated in nonhuman primates after a single subcutaneous dose and was compared to Bydureon. Exenatide release fr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Yazhou, Vaughan, Kelli L., Tweedie, David, Jung, Jin, Kim, Hee Kyung, Choi, Ho-Il, Kim, Dong Seok, Mattison, Julie A., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868133/
https://ncbi.nlm.nih.gov/pubmed/31748513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53356-2
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