Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

Microglia are the brain's immune cells and play an important role in regulating the microenvironment in the central nervous system. Activated microglia are capable of acquiring the pro-inflammatory (M1) phenotype and anti-inflammatory (M2) phenotype. Overactivation of microglia is neurotoxic an...

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Publicat a:Front Immunol
Autors principals: Liu, Bingrun, Huang, Bingxu, Hu, Guiqiu, He, Dewei, Li, Yuhang, Ran, Xin, Du, Jian, Fu, Shoupeng, Liu, Dianfeng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868066/
https://ncbi.nlm.nih.gov/pubmed/31798583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02650
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