CAR-Engineered NK Cells for the Treatment of Glioblastoma: Turning Innate Effectors Into Precision Tools for Cancer Immunotherapy

Glioblastoma (GB) is the most common and aggressive primary brain tumor in adults and currently incurable. Despite multimodal treatment regimens, median survival in unselected patient cohorts is <1 year, and recurrence remains almost inevitable. Escape from immune surveillance is thought to contr...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Burger, Michael C., Zhang, Congcong, Harter, Patrick N., Romanski, Annette, Strassheimer, Florian, Senft, Christian, Tonn, Torsten, Steinbach, Joachim P., Wels, Winfried S.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868035/
https://ncbi.nlm.nih.gov/pubmed/31798595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02683
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