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P12.04 Synergistic effects of combination therapy of CAR-NK cells and anti-PD-1 antibody result in high efficacy against advanced stage orthotopic glioblastoma grafts in a syngeneic mouse model and induce protective anti-tumor immunity in vivo

BACKGROUND: Checkpoint inhibitors as well as adoptive cell therapy hold great promise for cancer treatment and encouraging treatment responses have already been demonstrated in different cancer indications. Glioblastoma (GB) is the most common and aggressive primary brain tumor. Standard therapy has...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Strassheimer, F, Strecker, M I, Zhang, C, Mildenberger, I C, Harter, P N, Tonn, T, Steinbach, J P, Wels, W S, Burger, M C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796023/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.215
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