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P04.05 The CAR2BRAIN study: a monocentric phase I trial with ErbB2-specific NK-92/5.28.z cells in recurrent glioblastoma

Recent preclinical studies from our institutions and other researchers suggest that natural killer (NK) cells have the potential for adoptive immunotherapy of GBM. Like T cells, NK cells can be genetically modified to express chimeric antigen receptors (CARs) that recognize tumor-associated cell sur...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Burger, M. C., Mildenberger, I., Zhang, C., Ihrig, K., Wagner, M., Mittelbronn, M., Senft, C., Tonn, T., Wels, W. S., Steinbach, J. P.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782581/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.083
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