TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) play a crucial role in antiviral innate immunity through their unique capacity to produce large amounts of type I interferons (IFNs) upon viral detection. Tripartite motif (TRIM) proteins have recently come forth as important modulators of innate signaling, but th...

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Pubblicato in:Sci Adv
Autori principali: Maarifi, Ghizlane, Smith, Nikaïa, Maillet, Sarah, Moncorgé, Olivier, Chamontin, Célia, Edouard, Joanne, Sohm, Frédéric, Blanchet, Fabien P., Herbeuval, Jean-Philippe, Lutfalla, Georges, Levraud, Jean-Pierre, Arhel, Nathalie J., Nisole, Sébastien
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867881/
https://ncbi.nlm.nih.gov/pubmed/31799391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3511
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