Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria

Carbapenem-resistant Gram-negative bacteria are considered a major threat to global health. Imipenem (IMP) is used as a last line of treatment against these pathogens, but its efficacy is diminished by the emergence of resistance. We applied a whole-genome screen in Escherichia coli, Klebsiella pneu...

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Vydáno v:mSystems
Hlavní autoři: El Khoury, Jessica Y., Maure, Alexandra, Gingras, Hélène, Leprohon, Philippe, Ouellette, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867876/
https://ncbi.nlm.nih.gov/pubmed/31744905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00465-19
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