Targeting the unfolded protein response in head and neck and oral cavity cancers

Many FDA-approved anti-cancer therapies, targeted toward a wide array of molecular targets and signaling networks, have been demonstrated to activate the unfolded protein response (UPR). Despite a critical role for UPR signaling in the apoptotic execution of cancer cells by many of these compounds,...

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Publicado en:Exp Cell Res
Autores principales: Cole, Daniel W., Svider, Peter F., Shenouda, Kerolos G., Lee, Paul B., Yoo, Nicholas G., McLeod, Thomas M., Mutchnick, Sean A., Yoo, George H., Kaufman, Randal J., Callaghan, Michael U., Fribley, Andrew M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867800/
https://ncbi.nlm.nih.gov/pubmed/31075256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.04.007
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