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Targeting the unfolded protein response in head and neck and oral cavity cancers

Many FDA-approved anti-cancer therapies, targeted toward a wide array of molecular targets and signaling networks, have been demonstrated to activate the unfolded protein response (UPR). Despite a critical role for UPR signaling in the apoptotic execution of cancer cells by many of these compounds,...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Cole, Daniel W., Svider, Peter F., Shenouda, Kerolos G., Lee, Paul B., Yoo, Nicholas G., McLeod, Thomas M., Mutchnick, Sean A., Yoo, George H., Kaufman, Randal J., Callaghan, Michael U., Fribley, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867800/
https://ncbi.nlm.nih.gov/pubmed/31075256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.04.007
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