Targeting the unfolded protein response in head and neck and oral cavity cancers

Many FDA-approved anti-cancer therapies, targeted toward a wide array of molecular targets and signaling networks, have been demonstrated to activate the unfolded protein response (UPR). Despite a critical role for UPR signaling in the apoptotic execution of cancer cells by many of these compounds,...

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Bibliographic Details
Published in:Exp Cell Res
Main Authors: Cole, Daniel W., Svider, Peter F., Shenouda, Kerolos G., Lee, Paul B., Yoo, Nicholas G., McLeod, Thomas M., Mutchnick, Sean A., Yoo, George H., Kaufman, Randal J., Callaghan, Michael U., Fribley, Andrew M.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867800/
https://ncbi.nlm.nih.gov/pubmed/31075256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.04.007
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