Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response

Experimental study with human mesenchymal stem cells (MSCs) and intervertebral disc (IVD) tissue samples. OBJECTIVE. This study aimed to characterize the effect of MSC homing on the Tie2-positive IVD progenitor cell population, IVD cell survival, and proliferation. SUMMARY OF BACKGROUND DATA. Homing...

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Bibliographische Detailangaben
Veröffentlicht in:Spine (Phila Pa 1976)
Hauptverfasser: Wangler, Sebastian, Peroglio, Marianna, Menzel, Ursula, Benneker, Lorin M., Haglund, Lisbet, Sakai, Daisuke, Alini, Mauro, Grad, Sibylle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2019
Schlagworte:
Basic Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867676/
https://ncbi.nlm.nih.gov/pubmed/31730570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0000000000003150
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